Thermal optimized PCR coupled to CRISPR-Cas12a for rapid detection of blaOXA-1 resistance gene.
Quiroz-Huanca et al.,
PLoS One 2026 ;21(5)
The β-lactams are critically important broad-spectrum antibiotics, widely used as first-line treatments; however, their effectiveness is increasingly compromised by β-lactamase enzymes. Among these, OXA-type enzymes have expanded to over 400 varian...
Caloric restriction and aerobic exercise differentially counteract muscle-tendon dysfunction following diet-induced obesity in C57BL/6J mice.
Cesanelli et al.,
J Physiol 2026 May 15;()
Obesity profoundly impairs musculotendinous structure and function, but the extent to which these alterations can be reversed remains unclear. This study compared the effects of aerobic exercise (EX) and caloric restriction (CR) on the recovery of mu...
Integrated Assessment of Metal-Related Toxicity in a Sentinel Marine Plant, , Under Realistic Multi-Element Exposure.
Cocci et al.,
Int J Mol Sci 2026 Apr 29;27(9)
Mediterranean meadows of are chronically exposed to complex mixtures of environmental contaminants, including metals and trace elements derived from coastal urbanization, maritime traffic, and industrial activities. This study aimed to assess metal-...