Coordinated epigenetic dysregulation of CNR1 and FAAH genes drives endocannabinoid system dysfunction in anorexia nervosa.
Gilardini et al.,
J Eat Disord 2025 Nov 27;()
Anorexia nervosa (AN) is a severe psychiatric disorder with limited biomarkers for diagnosis and treatment monitoring. We investigated endocannabinoid system (ECS) dysregulation in AN through integrated epigenetic and genetic analysis of saliva....
Immunogenicity and Integration of a Decellularized Extracellular Matrix-Based Scaffold for the Reconstruction of Human Foreskin: A Preclinical Animal Study.
Pennasilico et al.,
Bioengineering (Basel) 2025 Oct 31;12(11)
The reconstruction of the foreskin using autografts is a complex procedure. A novel decellularisation method for epithelial tissue has been developed, producing an extracellular matrix scaffold from human donor foreskin. This study evaluated the immu...
Laxity index measurement on stress radiographs obtained using the Vezzoni-modified Badertscher distension device technique: repeatability and reproducibility in a large cohort of dogs.
Sassaroli et al.,
Front Vet Sci 2025 ;12()
The Vezzoni-modified Badertscher distension device (VMBDD) technique is a radiographic method used to assess hip joint laxity, and it is widely used across Europe. While the intra-observer and inter-observer variability of the laxity index (LI) measu...